دراسة فيتو كيميائية وتقييم النشاطية البيولوجية والعالجية لأطوار الفالفونويدات المستخلصة من ثمار نخيل البلح الفتية .صنف دقلة نور المزروع في منطقة وادي سوف

Abstract

The aims of this study to evaluate the biological and therapeutic efficacy of the phases of flavonoids extracted from young date palm fruits (Phoenix dactylifera L.) produced in the Oued Souf region. The flavonoids were extracted using four solvents for obtained (Diethyl ether, Ethyl acetate, 1-Butanol and aqueous phases). Their efficacy evaluated through a set of In Vitro tests. In terms of antioxidant activity in the tests DPPH, FRAP and CAT, the results showed that al extracted phases gave different values in exhibited the best antioxidant activity. In terms of anti-inflammatory activity by the test protein denaturation, the ethyl acetate phase proved to be the most effective. In vivo the white rats were male and their number was 18 rats experiments on rats evaluated the analgesic, anti-depressant and anti-ulcer effects. The aqueous and butanolic phases showed promising results in analgesic, antidepressant and preventing gastric ulcers. Together, these results indicate that the flavonoids extracted from date fruits possess important pharmacological properties: antioxidant, anti-inflammatory and analgesic, enhancing antidepressant and anti-anxiety and effective treatment of gastric ulcers, for all results making them a promising natural candidate for use in alternative medicine.