Thermodynamic Parameters Of Solutions Of Sildenafil Citrate In Some Organic Solvents At Different Temperatures

Abstract

The solubility of Sildenafilcitrate in someorganic solvents; hexane, toluene,1-butanol and 1,2 dichloroethanehas been determined using gravimetric method over different temperature range (298.15 K to 328.15 K) at one atmospheric pressure. The modified Apelblat and Buchowski-Ksiazczak λh equations were used to correlate the experimental solubility data.Further, various thermodynamic parameters have been evaluated from these solubility data.